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Question for April 01, 2002:

Information: Interpretation of cell sorting experiments.  

The use of cell sorting experiments with in situ hybridization and in situ PCR is a powerful combination.  In these experiments, cells were sorted into two groups - depending on the presence of a specific phenotypic marker.  These two groups were then analyzed for an IL mRNA.  Note that the first set has very rare + cells (figure #1), while in the second group most of the cells were + (figure #2).

Question: What are the possible interpretations?

Figure #1

Figure #2

 

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