 |
| Date | Opponent | Location | Time | Score | |
| 09/01 | Central Florida | Clemson, S.C. | 1:00 PM EDT | 21-13 | info |
| 09/08 | Wofford College | Clemson, S.C. | 1:00 PM EDT | 38-14 | info |
| 09/15 | Duke Game Postponed until 12/01 | ||||
| 09/22 | Virginia | Clemson, S.C. | 5:45 PM EDT ESPN2 |
24-26 | info |
| 09/29 | Georgia Tech | Atlanta, Ga. | 3:30 PM EDT ABC Regional |
47-44 | info |
| 10/06 | Open Date | ||||
| 10/13 | North Carolina State (Textile Bowl) |
Raleigh, N.C. | 12:00 PM EDT JP TV |
45-37 | info |
| 10/20 | North Carolina (Homecoming) |
Clemson, S.C. | 12:00 PM EDT ESPN2 |
3-38 | info |
| 10/27 | Wake Forest | Winston-Salem, N.C. | 12:00 PM EDT JP TV |
21-14 | info |
| 11/03 | Florida State ("Bowden Bowl") |
Clemson, S.C. | 3:30 PM EST ABC Regional |
27-41 | info |
| 11/10 | Maryland | College Park, Md. | 7:00 PM EST ESPN2 |
20-37 | info |
| 11/17 | South Carolina | Columbia, S.C. | 12:30 PM EST JP TV |
15-20 | info |
| 12/01 | Duke (Hall of Fame Day) |
Clemson, S.C. | 1:00 PM EST | 59-31 | info |
| 12/31 | Louisiana Tech Humanitarian Bowl |
Boise, ID | 12:30 PM EST ESPN |
49-24 | info |
 |
| Date | Opponent | Score | |
| 09/02 | The Citadel | 38-0 | |
| 09/09 | Missouri | 62-9 | |
| 09/16 | Wake Forest | 55-7 | |
| 09/23 | at Virginia | 31-10 | |
| 09/30 | at Duke | 55-22 | |
| 10/07 | North Carolina State | 34-27 | |
| 10/14 | Maryland | 35-14 | |
| 10/21 | at North Carolina | 38-24 | |
| 10/28 | Georgia Tech | 28-31 | |
| 11/04 | at Florida State | 7-54 | |
| 11/11 | Open Date | ||
| 11/18 | South Carolina | 16-14 | |
| 01/01 | Virginia Tech Gator Bowl |
20-41 | |